Wednesday
11:05 am12:20 pm (CDT) May 6, 2020

Concurrent Session III C: Translational Science in Vascular Medicine: Vascular Dysfunction

Organized in cooperation with the Council on Peripheral Vascular Disease


Access Sessions

11:05 am

Stem Cells for Preventing Vascular Injury

Sanjay Misra, MD, Mayo Clinic, Rochester, Minnesota

Rapid Fire Oral Abstracts

11:25 am   

Epigenetic Regulation of the Notch Signaling Pathway Modulates Macrophage/T Cell Phenotype and Impairs Diabetic Wound Healing  (140)

Frank Michael Davis, Aaron Dendekker, Amrita Joshi, Sonya Wolf, Bethany Moore, Katherine A Gallagher, Univ of Michigan, Ann Arbor, MI  

11:30 am  

Glycolysis Dictates the Reciprocal Activation Between Macrophages and Vascular Endothelial Cells in the Angiogenic Niche   (141)

Zhiping Liu, Jiean Xu, Qian Ma, Qiuhua Yang, Xiaoyu Zhang, Yuqing Huo, Augusta Univ, Augusta, GA  

11:35 am 

Differential Expression of Canonical Mitosis and Dna-damage Repair Pathways Characterize Muscle Satellite Cells Affected by Pad  (142)

Ricardo Ferrari, Guangzhi Cong, Bryan Thompson, Debbie Hollingshead, Janette Lamb, Xiangdong Cui, Ulka Sachdev, UPMC, Pittsburgh, PA  

11:40 am   

Single-Cell Transcriptomic Analysis Identifies Differences in Skeletal Muscle Macrophages in a Human Critical Limb Ischemia Patient and a Murine Model of Hindlimb Ischemia  (143)

Lindsey Olivere, Duke Univ Sch of Med, Durham, NC; Yu Xiang, James Otto, Timothy McCord, Christopher Kontos, Yarui Diao, Kevin Southerland, Duke Univ, Durham, NC

11:45 am   

The High Molecular Weight Isoforms of Fibroblast Growth Factor-2 are Necessary for Postischemic Hindlimb Functional Recovery and Revascularization  (144)

Adeola Adeyemo, Blake Stephens, Yu Zhang, Univ of Cincinnati, Cincinnati, OH; Jacob R Dale, Univ of Louisville, Louisville, KY; James B Hoying, Advanced Solutions Life Sciences, Louisville, KY; Jo El Schultz, Univ of Cincinnati, Cincinnati, OH  

11:50 am    

Dicer Modulation as a Mechanism of Age-Related Dysfunction in Arteriogenesis  (145)

Chris Sorel Mantsounga, Jade Neverson, VA Providence Medical Ctr, Providence, RI; Joshua Michael Berus, Brown Univ, Providence, RI; Cadence Lee, VA, Providence, RI; Abigail L Healy, VA, Providence, RI, Norwich, CT; Frank W Sellke, Brown Medical Sch, Providence, RI; Gaurav Choudhary, Providence VAMC, Brown Univ, Providence, RI; Alan R MORRISON, Alpert Medical Sch at Brown Univ, Providence, RI  

11:55 am

In vivo Identification of Sex-Specific Differences in Vascular Smooth Muscle Cell Gene Expression Programs  (146)

Audrey Cleuren, Martijn van der Ent, Isabelle Birt, Kristina Hunker, Santhi Ganesh, Univ of Michigan, Ann Arbor, MI  

Noon

Single-Cell Transcriptomic Profiling Identifies Dynamic Inflammatory and Regenerative Endothelial Cell Subpopulations Following Vascular Injury  (147)

Lianghui Zhang, Shang Gao, Zachary White, Yang Dai, Asrar B Malik, Jalees Rehman, Univ of Illinois at Chicago, Chicago, IL  

12:05 pm   

Brain Emotional Activity is Associated With Acute Plaque Instability via Enhanced Macrophage Activity: A Prospective 3d Rendered 18f Fdg-pet/ct Assessment  (148) 

Dong Oh Kang, Multimodal Imaging and Theranostic Lab, Cardiovascular Ctr, Korea Univ Guro Hosp, Seoul, Korea, Republic of; Jae Seon Eo, Dept of Nuclear Med, Korea Univ Guro Hosp, Seoul, Korea, Republic of; Eun Jin Park, Multimodal Imaging and Theranostic Lab, Cardiovascular Ctr, Korea Univ Guro Hosp, Seoul, Korea, Republic of; Hyeong Soo Nam, Dept of Mechanical Engineering, KAIST, Daejeon, Korea, Republic of; Joon Woo Song, Multimodal Imaging and Theranostic Lab, Cardiovascular Ctr, Korea Univ Guro Hosp, Seoul, Korea, Republic of; Cheol Ung Choi, Eung Ju Kim, Seung-Woon Rha, Hong Seog Seo, Cardiovascular Ctr, Korea Univ Guro Hosp, Seoul, Korea, Republic of; Hongki Yoo, Dept of Mechanical Engineering, KAIST, Daejeon, Korea, Republic of; Jin Won Kim, Multimodal Imaging and Theranostic Lab, Cardiovascular Ctr, Korea Univ Guro Hosp, Seoul, Korea, Republic of   

12:10 pm

Programmed Death Ligand-1 Regulates T-cells and M2 Macrophages to Control Wall Thickening During Arteriovenous Fistula Maturation

Yutaka Matsubara, Luis Gonzalez, Jia Liu, Arash Fereydooni, John Langford, Shin-rong Lee, Jolanta Gorecka, Mingjie Gao, Xixiang Gao, Ryosuke Taniguchi, Bogdan Yatsula, Alan Dardik, Dept of Surgery, Yale Univ Sch of Med, New Haven, CT  


12:15 pm 

Q&A/Wrap-up